CADRE members lead and participate in US and international research consortia. Below are listings of peer-reviewed publications that include CADRE members as lead or collaborating investigators.     

Recent publications 

Devanand et al. Intact global cognitive and olfactory ability predicts lack of transition to dementia. Alzheimers Dement. 2020  

He et al. Transmission of tauopathy strains is independent of their isoform composition.  Nat Commun. 2020

Kulick et al. Long-term exposure to ambient air pollution, APOE-e4 status, and cognitive decline in a cohort of older adults in northern Manhattan.  Environ Int. 2020

Reiman et al. Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study.  Nat Commun. 2020

Wheeler et al. Hadoop and PySpark for reproducibility and scalability of genomic sequencing studies.  Pac Symp Biocomput. 2020

Amlie-Wolf, et al. Inferring the Molecular Mechanisms of Noncoding Alzheimer’s Disease-Associated Genetic Variants.  J Alzheimers Dis. 2019

Avila et al. Sex/gender differences in cognitive trajectories vary as a function of race/ethnicity. Alzheimers Dement. 2019

Baker et al. Gene-based analysis in HRC imputed genome wide association data indentifies three novel genes for Alzheimer’s disease. PLoS  One 2019 

Choi et al. APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE e4 on Alzheimer’s Disease Risk in a Multiracial Sample. J Clin Med. 2019

Devanand et al.  Intact global cognitive and olfactory ability predicts lack of transition to dementia. Alzheimers Dement. 2019

Dumitrescu et al. Sex differences in the genetic predictors of Alzheimer’s pathology. Brain. 2019

Feliciano-Astacio et al. The Puerto Rico Alzheimer Disease Initiative (PRADI): A Multisource Ascertainment Approach. Front Genet. 2019

Gardner et al. RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways. Hum Mol Genet. 2019

Goldschmidt-Clermont et al. Time for Well-Powered Controlled Prospective Studies to Test a Causal Role for Herpes Viruses in Alzheimer’s Disease Using Antiherpetic Drugs. J Gerontol A  Biol Sci Med Sci. 2019

Gutierrez et al. Brain arterial dilatation and the risk of Alzheimer’s disease. Alzheimers Dement. 2019

Kunkle et al. Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Ab, tau, immunity and lipid processing. Nat Genet. 2019

Leung et al. VCPA: genomic variant calling pipeline and data management tool for Alzheimer’s Disease Sequencing Project. Bioinformatics. 2019

Ma et al. Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype. JAMA Neurol. 2019

Ma et al. CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease. Aging Cell. 2019

Naj et al. Quality Control and Integration of Genotypes from Two Calling Pipelines for Whole Genome Sequence Data in the Alzheimer’s Disease Sequencing Project. Genomics. 2019

Ogino et al. Current and past leisure time physical activity in relation to risk of Alzheimer’s disease in older adults. Alzheimers Dement. 2019

Patel et al. Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry. JAMA Netw Open. 2019

Sariya et al. Rare Variants Imputation in Admixed Populations: Comparison Across Reference Panels and Bioinformatics Tools. Front Genet. 2019

Stamm et al. Parental History of Dementia Is Associated with Increased Small Vessel Cerebrovascular Disease. J Gerontol A Biol Sci Med Sci. 2019

Tosto et al. Association of Variants in PINX1 and TREM2 With Late-Onset Alzheimer Disease. JAMA Neurol. 2019

Vonk et al. Education Moderates the Relation Between APOE e4 and Memory in Nondemented Non-Hispanic Black Older Adults. J Alzheimers Dis. 2019

Vonk et al. Secular trends in cognitive trajectories of diverse older adults. Alzheimers Dement. 2019

Zhang et al. A rare missense variant of CASP7 is associated with familial late-onset Alzheimer’s disease. Alzheimers Dement. 2019

Zhang et al. Genetic and epigenetic study of an Alzheimer’s disease family with monozygotic triplets. Brain. 2019