Leaders in Alzheimer's Disease Genomics

We Bring Breadth and Depth of Experience to the Table 

All of us have collaborated on large-scale genetics projects and all of us have been involved in identifying novel  genetic variations and biological pathways implicated in Alzheimer’s Disease – or disease resistance.  We are founding members of the Alzheimer’s Disease Genetics Consortium (ADGC), the Alzheimer’s Disease Sequencing Project (ADSP), and the International Genomics of Alzheimer’s Project (IGAP).  

Executive Committee

Jonathan Haines, PhD

Jonathan Haines, PhD

The Cleveland Institute for Computational Biology at Case Western Reserve University School of Medicine
CADRE: Contact MPI, strategic leadership; multi-locus analysis

Margaret (Peggy) Pericak-Vance, PhD

Margaret (Peggy) Pericak-Vance, PhD

John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine
CADRE: MPI, strategic leadership; association analysis

Lindsay Farrer, PhD

Lindsay Farrer, PhD

Boston University School of Medicine
CADRE: MPI, epigenetic and mitochondrial analysis

William (Will) S. Bush, PhD

William (Will) S. Bush, PhD

The Cleveland Institute for Computational Biology at Case Western Reserve University School of Medicine
CADRE: MPI, bioinformatics analysis, variant prioritization, and drug target prioritization

Eden Martin, PhD

Eden Martin, PhD

John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine
CADRE: MPI, assessment of local ancestry and genetic fine mapping

Richard Mayeux, MD, MsC

Richard Mayeux, MD, MsC

Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, at Columbia University
CADRE: Neurological phenotypes and family studies of Caribbean populations

Gerard Schellenberg, PhD

Gerard Schellenberg, PhD

Penn Neurodegeneration Genomics Center at the University of Pennsylvania Perelman School of Medicine
CADRE: Strategic leadership, functional genomics
NIGADS: Investigators
ADGC: Principle Investigator

 

Li-San Wang, PhD

Li-San Wang, PhD

Penn Neurodegeneration Genomics Center at the University of Pennsylvania Perelman School of Medicine
CADRE: Data management and variant calling
NGADS: Principle Investigator
GCAD: Co-director

CADRE Investigators

Gary Beecham, PhD

Gary Beecham, PhD

John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine
CADRE: Assessment of local ancestry and genetic fine mapping

Gyungah Jun, PhD

Gyungah Jun, PhD

Boston University School of Medicine
CADRE: Biological pathway and drug target identification

Brian Kunkle, PhD

Brian Kunkle, PhD

John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine
CADRE: Statistical analysis of genetic data

Adam Naj, PhD

Adam Naj, PhD

University of Pennsylvania Perelman School of Medicine
CADRE: Quality control and statistical analysis of genetic data
NIGADS: Investigator

Timothy A. Thorton, PhD

Timothy A. Thorton, PhD

School of Public Health, University of Washington
CADRE: Statistic methods for ancestry analysis

Badri N. Vadarajan, PhD, MS

Badri N. Vadarajan, PhD, MS

Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, at Columbia University
CADRE: Admixture analysis in Caribbean populations

 Xiaoling Zhang, PhD

Xiaoling Zhang, PhD

Boston University School of Medicine
CADRE: Mitochondrial and X-linked genetic analysis

Additional Collaborators

Clifton Dalgard, PhD

Amanda Kuzma, PhD

Yuk Yee (Fanny) Leung, PhD

Farid Rejabli, PhD

Institutions

Supported by Leading Academic Institutions in the U.S.