Leading the data analysis for the Alzheimer's Disease Sequencing Project

CADRE: The Collaborative for Alzheimer’s Disease Research
Our ResearchOur Investigators

A national initiative

 Alzheimer’s Disease is the most common neurodegenerative disease in the US, affecting more than 35% of people age 85 and older. Current drugs have only a marginal and temporary effect on Alzheimer’s Disease progression. Our goal is to use state of the art genomics data to discover new drug targets for this devastating disease. 

Institutional Support and Resources

CADRE is focused on analyses of data generated by the Alzheimer’s Disease Sequencing Project – a national collaboration with data representing tens of thousands of individuals and/or related family members.  


Our goal is to enhance understanding of the genetic architecture of this disease and to accelerate the search for new therapeutic targets. Our work is inclusive of populations that historically have not been represented in large genetic studies.


Our investigators are affiliated with multiple academic institutions and have made seminal discoveries in the genetics of Alzheimer’s Disease.  They now focus their collective scientific efforts on this new national initiative. 

CADRE is administratively housed at Case Western Reserve University with support from all participating academic institutions

Department of Population and Quantitative Health Sciences

2103 Cornell Road, Suite 2500

Cleveland, Ohio 44106